Nineteen of the Russian's 21 titles have been won on hard surfaces
A revitalized the Russian player won his initial title for nearly 30 months with victory over Corentin Moutet in the competition championship match.
The athlete, a ex- number one, has endured a challenging period, managing just one match at the major tournaments and undergoing a difficult moment at the American major.
The player's inconsistency on the tennis tour - and difficulties with his service game in specific - caused him exiting of the elite rankings and ultimately splitting with former coach his previous coach.
Presently training with Johansson and Goetzke, the tennis star has steadily progressed in the past month - peaking in a closely contested three-set triumph over opponent Moutet.
It is his initial trophy following the Rome competition and initial on a hard surface since that period of that year.
Victory also means Medvedev has secured twenty-one championships at twenty-one distinct competitions.
"For the first time I have attended a tournament with my children simultaneously, so to get a title is particularly special," said world number 14 the champion.
"This victory is in tribute of my younger daughter my daughter, because the maiden victory I won when my first daughter my daughter was born was for her."
The athlete, the former major winner, had failed in his previous six finals, featuring in the German tournament earlier this year.
His counter-punching strategy and recurring reactions on court had prompted observers to wonder if his capacity to play at the elite level was finished.
But the player has implemented adjustments in the last few weeks, striving to approach the net and compete assertively, reinforced by an enhanced serve.
The champion recovered from a disadvantage in the first set against the tricky Frenchman, winning 4 of the concluding five games to gain the advantage.
The pair swapped break points in the middle set before the challenger, attempting for his maiden ATP Tour championship, gained dominance to push for a third set.
The opponent defended four early-game chances in a competitive deciding set before the Russian won the break to 15 to secure the win.
Suitably, the winner earned the win with a point at the net area, with the Frenchman failing to handle a return after over two and a half hours.